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How-To Guide

How to Write a Systematic Literature Review in Nursing

What makes a review systematic, the PRISMA 2020 flow, protocol steps, appraisal tools such as CASP and JBI, and how to tell whether your assignment needs one.

Updated October 2026 · 7 min read

In nursing research, "systematic review" names a specific method, not just a thorough literature review. It has a pre-set protocol, explicit criteria, formal appraisal and its own reporting standard.

This guide explains how a systematic review differs from a narrative review, walks through the protocol and the PRISMA 2020 flow, covers appraisal tools, and helps you decide whether your assignment really asks for one.

What Makes a Review Systematic

A systematic review answers a focused question using a protocol set before searching: named databases, search strings, dates and inclusion criteria. Every record is screened against those criteria, every included study is formally appraised, and the process is reported with the PRISMA 2020 checklist and flow diagram.

If your assignment does not mention PRISMA or formal appraisal, it probably wants a well-organized narrative review instead.

Systematic Versus Narrative Review

A narrative review, the kind most capstone Chapter 2s use, synthesizes research around a topic by theme. The reviewer uses judgment to choose studies that inform the argument.

A systematic review is a research method in its own right. Its decisions are documented before searching so that another researcher could repeat the search and reach the same set of studies.

FeatureNarrative reviewSystematic review
SearchExploratory, may evolve while readingPre-specified databases, search strings and date range, documented in full
SelectionReviewer judgment on relevanceExplicit criteria applied to every record, with exclusions counted
AppraisalOften informalFormal appraisal of every included study with a standard tool
ReportingNo required standardPRISMA 2020 checklist and flow diagram
ScopeA section or chapter of a larger paperOften a standalone paper or a full dedicated chapter
ReproducibilityNot designed to be repeated exactlyDesigned to be repeatable

The practical point: a systematic review is a different kind of document with its own methods section, not a longer version of a background chapter.

Core Steps in a Systematic Review Protocol

The protocol is written before you search. Changing criteria after you have read the studies introduces exactly the selection bias the method is designed to prevent.

  1. Define a focused question, usually with PICOT or PICo for qualitative questions.
  2. Set inclusion and exclusion criteria: population, intervention or exposure, comparison, outcomes, study designs, dates and language.
  3. Name the databases and write the exact search strings.
  4. Run the searches, record results per database and remove duplicates.
  5. Screen titles and abstracts against the criteria and record exclusions.
  6. Retrieve full texts, apply the criteria again and record each exclusion reason.
  7. Appraise each included study with a tool matched to its design.
  8. Extract data into a standard table and synthesize the findings.

Most nursing reviews search at least two or three databases. CINAHL and PubMed/MEDLINE are the usual core, with the Cochrane Library added for intervention questions and PsycINFO for mental health topics.

Combine subject headings (CINAHL Headings, MeSH) with keywords and synonyms. Join synonyms with OR and concepts with AND, then record the final string for each database exactly as run.

Illustrative PubMed string for a falls question:

("Accidental Falls"[MeSH] OR fall* ) AND ("Hospitals"[MeSH] OR inpatient* OR "acute care") AND (rounding OR "intentional rounding" OR "hourly rounding") AND ("Aged"[MeSH] OR "older adult*")

Limits applied: English language, 2019 to 2024, peer-reviewed. The CINAHL version would use CINAHL Headings in place of MeSH terms.

Test the string before committing. A search that returns thousands of records may be too broad to screen; one that returns a handful may be missing synonyms.

The PRISMA 2020 Flow Diagram

PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) was updated in 2020. Its flow diagram tracks records through three main stages.

StageWhat you report
IdentificationRecords found in each database and other sources; duplicates and other records removed before screening
ScreeningRecords screened by title and abstract and how many excluded; reports sought and retrieved; full texts assessed and excluded, with reasons
IncludedStudies included in the review, and in any meta-analysis

Older guides describe a separate eligibility stage from the 2009 version. PRISMA 2020 folds full-text assessment into screening, so use the current template unless your course specifies otherwise.

The diagram is also a planning tool. If 800 records shrink to four included studies, your terms or criteria may need adjusting before you spend hours on full texts.

Check that the numbers add up from stage to stage. Mismatched totals are one of the first things markers notice.

Quality Appraisal with CASP and JBI

Formal appraisal of every included study is a defining feature of a systematic review. Many nursing programs introduce it through two families of checklists.

Match the tool to each study's design; an RCT checklist does not fit a qualitative study. Present the results in a table showing how each study met each criterion.

Then use the appraisal. A weaker study can still be included when evidence is limited, but your synthesis should give it less weight and say so openly.

Synthesizing the Findings

Extract the same data from every study: author and year, design, sample and setting, intervention, outcomes, key findings and appraisal result. A consistent extraction table makes the synthesis much easier to write.

Most student reviews use narrative synthesis, grouping findings by outcome or theme and comparing direction and strength of effect. A meta-analysis pools results statistically and only makes sense when studies are similar enough in design, population and measures.

Qualitative reviews use approaches such as thematic synthesis. Whatever the method, end with what the body of evidence supports, its limits, and what it means for practice.

Does Your Assignment Need a True Systematic Review?

Doing a full systematic review when a narrative review was expected wastes weeks. Submitting a narrative review when a systematic one was required misses large parts of the rubric.

Signals that a true systematic review is expected:

If "systematic" is used loosely to mean thorough, a well-organized narrative review is usually right; our nursing literature review guide covers that format. When in doubt, ask your instructor whether PRISMA reporting and formal appraisal are expected.

Common Systematic Review Mistakes

These problems are flagged quickly by markers who know the method. Most come from treating the review as an ordinary literature search.

How NurseCapstone Helps with Systematic Reviews

Send your assignment prompt, your question and any required databases or appraisal tools. A writer matched to your level confirms whether the brief calls for a systematic or narrative review, then drafts a model with a documented protocol, search log, PRISMA 2020 flow, appraisal tables and synthesis.

The model is built on real, verifiable sources and never invented data. Use it to guide your own review, with free revisions within the scope of your original request.

Need a Model Systematic Review?

Share your prompt, PICOT question and required databases. You get a model with a search protocol, PRISMA reporting and synthesis to guide your own.

Start My Systematic Review

Free revisions · Full refund if late · Written from scratch for your order

Frequently Asked Questions

How is a systematic review different from a DNP literature review?

Most DNP literature reviews are narrative and thematic. A systematic review adds a pre-set protocol, documented screening, formal appraisal of every study and PRISMA reporting.

Do I need to register my protocol on PROSPERO?

Registration is uncommon for student assignments. You should still document your criteria, databases and search strings before searching.

How many databases should I search?

Usually at least two or three, commonly CINAHL and PubMed/MEDLINE, with the Cochrane Library added for intervention questions.

What if my search returns very few results?

Your question may be too narrow or your terms too specific. Try synonyms, related subject headings or a wider date range, as long as the review still answers your question.

Do I need a second reviewer?

Published reviews normally use two independent screeners. Individual student assignments usually accept one reviewer, but check your program's expectations.

Can a systematic review include qualitative studies?

Yes. Qualitative and mixed-methods reviews are common in nursing; use an appraisal tool that matches each study's design.

What is the difference between a systematic review and a meta-analysis?

A meta-analysis statistically pools results across studies. Many systematic reviews do not include one, especially when studies are too different to combine.

How long does a student systematic review take?

Much longer than a narrative review. Searching, screening and appraisal can take several weeks before synthesis writing begins, so start early.